MotoGP has been home to some of the most iconic manufacturers in the world, and the competition between them has shaped the sport into what it is today. The Constructors' Title is awarded to the manufacturer whose bikes have accumulated the most points over the course of a season. Below is a ranking based on the number of Constructors' Championships each manufacturer has won.

1. Honda

Founded: 1948
Titles: 25

Honda is, without a doubt, the leader when it comes to MotoGP Constructors' Championships, with an impressive 25 titles. Since entering the sport, Honda has been a dominant force in the paddock, often developing bikes that are both fast and highly competitive. Their bikes, particularly the RC211V and RC213V, have been race-winning machines, powered by legendary riders like Marc Márquez, Mick Doohan, and Dani Pedrosa. Honda’s innovation and commitment to excellence have made them a consistent front-runner in the sport.

• Notable Champions: Marc Márquez, Mick Doohan, Dani Pedrosa

2. MV Agusta

Founded: 1945
Titles: 16

MV Agusta, though not a major name in recent years, holds an impressive history with 16 Constructors' Titles. Their dominance in the 1950s and 1960s, especially under the guidance of legendary riders like Giacomo Agostini, helped the brand establish its legacy in MotoGP history. MV Agusta was a force to be reckoned with during the early years of the sport. Though they are not active in MotoGP today, their legacy in the sport is firmly cemented.

• Notable Champions: Giacomo Agostini

3. Yamaha

Founded: 1953
Titles: 14

Yamaha ranks third with 14 Constructors' Titles. Known for producing some of the most popular bikes in the sport, such as the YZR-M1, Yamaha has been highly competitive in MotoGP for decades. Their success can be attributed to remarkable riders like Valentino Rossi and Jorge Lorenzo, who each won multiple world titles with the brand. Yamaha has had a strong presence in the sport since the early 2000s and continues to be a major competitor in the championship.

• Notable Champions: Valentino Rossi, Jorge Lorenzo, Fabio Quartararo

4. Suzuki

Founded: 1909
Titles: 7

Suzuki may not have as many titles as some of the other manufacturers on this list, but with 7 Constructors' Titles, they remain a brand to be remembered. Suzuki’s bikes, such as the GSX-RR, have been highly competitive in the recent era. The brand produced some memorable moments, particularly during the 2020 season, before they left MotoGP. Kenny Roberts Jr. and Joan Mir helped bring Suzuki back to the top of the sport, proving their ability to build winning motorcycles.

• Notable Champions: Kenny Roberts Jr., Joan Mir

5. Ducati

Founded: 1926
Titles: 6

Ducati has had a roller-coaster journey in MotoGP, but with 6 Constructors' Titles, they have certainly made their mark. The Desmosedici GP series has proven to be a competitive machine, and Ducati has enjoyed periods of dominance, especially in recent years with the rise of Francesco Bagnaia. Ducati is known for its innovative engineering and unique designs. While they may have fewer titles compared to the top manufacturers, their influence in the sport cannot be denied.

• Notable Champions: Casey Stoner, Francesco Bagnaia